Capo d'Africa is one of the best EU hotels we ever stayed at, so I'll start with Capo d'Africa's only fault-- in a city of overpriced hotels, this one is really over priced.
Capo d'Africa is located in a quiet residential neighborhood about 3 blocs from the Coliseum and a major bus stop, and 5 blocks from Metro. Here's what's good about it: its quiet. Its on a quiet street. The interior is quiet unless your room is next to the elevator. Standard rooms are, well, standard as the EU goes, meaning they are a bit on the small side. We had a Superior room-- lots of space, a comfortable arm chair, good bed & pillows, quiet, drapes that did a good job darkening the room, multi channel TV, distant but effective desk/concierge
The best pizza we ever had came from a hole in the wall joint about two blocks away. Being in a residential neighborhood, we had a choice of authentic local restaurants, and that's where we first started to realize that Italian cooking often falls short of its reputation.
Perhaps the highlight of our stay at Capo d'Africa was discovering Limoncello at the booze store down the block.
The buffet breakfast was excellent and served on the roof top (indoors or outdoors) with nice views over the city.
We arrived at the Capo d'Africa during Italian Culture week, which turns out to mean there is no admission charge to visit the Colosseum, the Forum, the Palatine Hill, and the Capitoline museums. The entrance to all these except the Capitoline Hill was only 3-4 blocks from Capo d'Africa.
In culture Week, which comes in the spring, slightly different dates every year, admission to all heritage sights owned by the Italian government is free.
Enjoy a private 3 hour tour (max 6 people) of the Vatican Museums including the Raphael Rooms and The Sistine Chapel ending with a privileged entrance to St.Peter's Basilica. Highlights include the Belvedere courtyard, Pine courtyard, Gallery of Maps ,Gallery of Tapestries, Pio Clemente museum and the Raphael Rooms.